A wheelchair is a chair with wheels attached on its sides.
- Lydia uses a wheelchair because she has been unable to move her legs since birth.
- Brain had a wheelchair that kept his right leg raised while he recovered from an injury. He transitioned to using crutches soon after.
- There is also a rabbit girl who uses a wheelchair.
- Dr. Zimmer started using a wheelchair now that he lives at Shady Pines Retirement Home.
- In D.W.'s imagination, she and Arthur would keep arguing with each other about the soufflé even when they were in wheelchairs and living in a retirement home.
- Jenna helps out the wheelchair basketball team, despite not using one herself.
- Mr. Ronzini uses a wheelchair.
- "Arthur's Family Feud"
- "The Good Sport" (mentioned only)
- "Prunella Sees the Light" (mentioned only)
- "The Wheel Deal"
- "Buster's Garden of Grief"
- "Little Miss Meanie"